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facts about simvastatin

simvastatin

simvastatin

simvastatin

Simvastatin (a derivative of lovastatin and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl coa reductases), which is the rate-limiting enzyme in cholesterol biosynthesis)

class, substance, drug, statin, medical concept, cause, Hydroxymethylglutaryl CoA reductase inhibitors, Drugs, hormones and biological mediators
ATC code, ATC Code
"C10AA01"
CAS registry_number, CAS Code
"79902-63-9"
Side effects
myalgia, rhabdomyolysis, myopathy
Class
drug; statin; Hydroxymethylglutaryl CoA reductase inhibitors; substance; Drugs, hormones and biological mediators;  …
Parent Class
drug, Hydroxymethylglutaryl CoA reductase inhibitors
Wikipedia Page
http://en.wikipedia.org/wiki/Simvastatin
Providers
Merck & Co.
Interacts with
Warfarin, Erythromycin, amiodarone, Clarithromycin, Cyclosporin,  …
Cause of
rhabdomyolysis, myalgia, myopathy, Cytochrome P450 substrate, Creatine kinase levels raised (plasma or serum)
Freebase ID
"/guid/9202a8c04000641f80000000002f1048"
Related Websites
http://druginfo.nlm.nih.gov/drugportal/dpdirect.jsp?name=Simvastatin, http://www.rxlist.com/cgi/generic/simva.htm
DBPedia URI
http://dbpedia.org/resource/Simvastatin
Mesh ID
"D019821"
Diseases DB id
"12128"
Contra-indications
pregnancy, Acute intermittent porphyria
Interacting Substances
amiodarone, Telithromycin
Freebase Primary MID
"/m/02z428"
Tell me what you know about simvastatin, a hypolipidemic drug used to control elevated cholesterol, or hypercholesterolemia.
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External web pages (using standard web search):

A-Z Drug Facts for the Professional; Drug Interactions Checker; Patient CareNotes for the ... Simvastatin (Zocor) belongs to a group of drugs called HMG CoA reductase inhibitors, or ...
All about Simvastatin Tablets. View complete and up to date Simvastatin information - part of the Drugs.com trusted medication database.
Facts and figures about Simvastatin, taken from Freebase, the world's database.
MRC/BHF Heart Protection Study : Facts about Statins ... Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Lipostat), simvastatin ...
Simvastatin vs Lipitor is a possible challenge due to the fact that both drugs are statins that are used to reduce cholesterol levels. The comparison of Simvastatin vs Lipitor ...

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